Dendrimer-Based MRI Contrast Agents: The Effects of PEGylation on Relaxivity and Pharmacokinetics

Polyethylene glycol (PEG)-surface modification can make nano-materials highly hydrophilic, reducing sequestration in the reticuloendothelial system. In this study, polyamidoamine (PAMAM) dendrimers bearing gadolinium chelates were PEGylated with different PEG-chain lengths and the effects on paramag...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kojima, Chie, Turkbey, Baris, Ogawa, Mikako, Bernardo, Marcelino, Regino, Celeste A. S., Bryant, L. Henry, Choyke, Peter L., Kono, Kenji, Kobayashi, Hisataka
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159711/
https://ncbi.nlm.nih.gov/pubmed/21515406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.03.007
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