Preparation and long-term biodistribution studies of a PAMAM dendrimer G5–Gd-BnDOTA conjugate for lymphatic imaging

AIMS: To demonstrate the use of gadolinium (Gd)-labeled dendrimers as lymphatic imaging agents and establish the long-term biodistribution (90-day) of this type of agent in mice. MATERIALS & METHODS: A G5-Gd-BnDOTA dendrimer was prepared and injected into mice and monkeys for MR lymphangiography...

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Vydáno v:Nanomedicine (Lond)
Hlavní autoři: Opina, Ana Christina, Wong, Karen J, Griffiths, Gary L, Turkbey, Baris I, Bernardo, Marcelino, Nakajima, Takahito, Kobayashi, Hisataka, Choyke, Peter L, Vasalatiy, Olga
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482252/
https://ncbi.nlm.nih.gov/pubmed/25392239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.14.113
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