載入...
Human ADPKD primary cyst epithelial cells with a novel PKD1 mutation exhibit defective ciliary polycystin localization and loss of flow-induced Ca(2+) signaling
ADPKD gene products polycystin-1 (PC1) and polycystin-2 (PC2) colocalize in the apical monocilia of renal epithelial cells. Mouse and human renal cells without PC1 protein show impaired ciliary mechanosensation, and this impairment has been proposed to promote cystogenesis. However, most cyst epithe...
Na minha lista:
| Main Authors: | , , , , , , , |
|---|---|
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3586432/ https://ncbi.nlm.nih.gov/pubmed/17090781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00285.2006 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|