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Mechanistic Studies of Wacker-Type Amidocyclization of Alkenes Catalyzed by (IMes)Pd(TFA)(2)(H(2)O): Kinetic and Stereochemical Implications of Proton Transfer()

The stereochemical course of the amidopalladation of alkenes has important implications for the development of enantioselective Pd-catalyzed “Wacker-type” oxidative amination of alkenes. We have recently shown that the addition of base (Na(2)CO(3)) can alter the stereochemical course of amidopallada...

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Bibliographic Details
Main Authors: Ye, Xuan, White, Paul B., Stahl, Shannon S.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586306/
https://ncbi.nlm.nih.gov/pubmed/23157332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo302266t
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