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Pathogenic Role of Basic Calcium Phosphate Crystals in Destructive Arthropathies

BACKGROUND: basic calcium phosphate (BCP) crystals are commonly found in osteoarthritis (OA) and are associated with cartilage destruction. BCP crystals induce in vitro catabolic responses with the production of metalloproteases and inflammatory cytokines such as interleukin-1 (IL-1). In vivo, IL-1...

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Hlavní autoři: Ea, Hang-Korng, Chobaz, Véronique, Nguyen, Christelle, Nasi, Sonia, van Lent, Peter, Daudon, Michel, Dessombz, Arnaud, Bazin, Dominique, McCarthy, Geraldine, Jolles-Haeberli, Brigitte, Ives, Annette, Van Linthoudt, Daniel, So, Alexander, Lioté, Frédéric, Busso, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585350/
https://ncbi.nlm.nih.gov/pubmed/23468973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057352
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