Pathogenic Role of Basic Calcium Phosphate Crystals in Destructive Arthropathies

BACKGROUND: basic calcium phosphate (BCP) crystals are commonly found in osteoarthritis (OA) and are associated with cartilage destruction. BCP crystals induce in vitro catabolic responses with the production of metalloproteases and inflammatory cytokines such as interleukin-1 (IL-1). In vivo, IL-1...

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Autors principals: Ea, Hang-Korng, Chobaz, Véronique, Nguyen, Christelle, Nasi, Sonia, van Lent, Peter, Daudon, Michel, Dessombz, Arnaud, Bazin, Dominique, McCarthy, Geraldine, Jolles-Haeberli, Brigitte, Ives, Annette, Van Linthoudt, Daniel, So, Alexander, Lioté, Frédéric, Busso, Nathalie
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585350/
https://ncbi.nlm.nih.gov/pubmed/23468973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057352
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