Pathogenic Role of Basic Calcium Phosphate Crystals in Destructive Arthropathies

BACKGROUND: basic calcium phosphate (BCP) crystals are commonly found in osteoarthritis (OA) and are associated with cartilage destruction. BCP crystals induce in vitro catabolic responses with the production of metalloproteases and inflammatory cytokines such as interleukin-1 (IL-1). In vivo, IL-1...

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Main Authors: Ea, Hang-Korng, Chobaz, Véronique, Nguyen, Christelle, Nasi, Sonia, van Lent, Peter, Daudon, Michel, Dessombz, Arnaud, Bazin, Dominique, McCarthy, Geraldine, Jolles-Haeberli, Brigitte, Ives, Annette, Van Linthoudt, Daniel, So, Alexander, Lioté, Frédéric, Busso, Nathalie
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585350/
https://ncbi.nlm.nih.gov/pubmed/23468973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057352
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