Pathogenic Role of Basic Calcium Phosphate Crystals in Destructive Arthropathies

BACKGROUND: basic calcium phosphate (BCP) crystals are commonly found in osteoarthritis (OA) and are associated with cartilage destruction. BCP crystals induce in vitro catabolic responses with the production of metalloproteases and inflammatory cytokines such as interleukin-1 (IL-1). In vivo, IL-1...

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Detalhes bibliográficos
Main Authors: Ea, Hang-Korng, Chobaz, Véronique, Nguyen, Christelle, Nasi, Sonia, van Lent, Peter, Daudon, Michel, Dessombz, Arnaud, Bazin, Dominique, McCarthy, Geraldine, Jolles-Haeberli, Brigitte, Ives, Annette, Van Linthoudt, Daniel, So, Alexander, Lioté, Frédéric, Busso, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585350/
https://ncbi.nlm.nih.gov/pubmed/23468973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057352
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