Asymmetric Dimethylarginine Induces Endothelial Nitric-oxide Synthase Mitochondrial Redistribution through the Nitration-mediated Activation of Akt1

We have recently demonstrated that asymmetric dimethylarginine (ADMA) induces the translocation of endothelial nitric-oxide synthase (eNOS) to the mitochondrion via a mechanism that requires protein nitration. Thus, the goal of this study was elucidate how eNOS redistributes to mitochondria and to i...

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Detalhes bibliográficos
Main Authors: Rafikov, Ruslan, Rafikova, Olga, Aggarwal, Saurabh, Gross, Christine, Sun, Xutong, Desai, Julin, Fulton, David, Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585057/
https://ncbi.nlm.nih.gov/pubmed/23255608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.423269
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