Protein engineering to develop a redox insensitive endothelial nitric oxide synthase()

The zinc tetrathiolate (ZnS(4)) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with a Zn ion in the center of a tetrahedral conf...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Rafikov, Ruslan, Kumar, Sanjiv, Aggarwal, Saurabh, Pardo, Daniel, Fonseca, Fabio V., Ransom, Jessica, Rafikova, Olga, Chen, Qiumei, Springer, Matthew L., Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297941/
https://ncbi.nlm.nih.gov/pubmed/25460726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.12.015
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