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Protein engineering to develop a redox insensitive endothelial nitric oxide synthase()

The zinc tetrathiolate (ZnS(4)) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with a Zn ion in the center of a tetrahedral conf...

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Bibliografiske detaljer
Udgivet i:Redox Biol
Main Authors: Rafikov, Ruslan, Kumar, Sanjiv, Aggarwal, Saurabh, Pardo, Daniel, Fonseca, Fabio V., Ransom, Jessica, Rafikova, Olga, Chen, Qiumei, Springer, Matthew L., Black, Stephen M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4297941/
https://ncbi.nlm.nih.gov/pubmed/25460726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.12.015
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