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Protein engineering to develop a redox insensitive endothelial nitric oxide synthase()
The zinc tetrathiolate (ZnS(4)) cluster is an important structural feature of endothelial nitric oxide synthase (eNOS). The cluster is located on the dimeric interface and four cysteine residues (C94 and C99 from two adjacent subunits) form a cluster with a Zn ion in the center of a tetrahedral conf...
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| Udgivet i: | Redox Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4297941/ https://ncbi.nlm.nih.gov/pubmed/25460726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.12.015 |
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