Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury.

Lipopolysaccharide (LPS) derived from the outer membrane of gram-negative bacteria induces acute lung injury (ALI) in mice. This injury is associated with lung edema, inflammation, diffuse alveolar damage, and severe respiratory insufficiency. We have previously reported that LPS-mediated nitric oxi...

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Main Authors: Christine M Gross, Ruslan Rafikov, Sanjiv Kumar, Saurabh Aggarwal, P Benson Ham, Mary Louise Meadows, Mary Cherian-Shaw, Archana Kangath, Supriya Sridhar, Rudolf Lucas, Stephen M Black
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4364989?pdf=render
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