Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations

Multiple lines of evidence support a role for curcumin in cancer chemoprevention. Nonetheless, despite its reported efficacy and safety profile, clinical translation of curcumin has been hampered by low oral bioavailability, requiring infeasible ‘mega’ doses for achieving detectable tissue levels. W...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Chun, Yong Soon, Bisht, Savita, Chenna, Venugopal, Pramanik, Dipankar, Yoshida, Takahiro, Hong, Seung-Mo, de Wilde, Roeland F., Zhang, Zhe, Huso, David L., Zhao, Ming, Rudek, Michelle A., Stearns, Vered, Maitra, Anirban, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584967/
https://ncbi.nlm.nih.gov/pubmed/22831956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs248
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados