A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl(4)-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation

Plant-derived polyphenols such as curcumin hold promise as a therapeutic agent in the treatment of chronic liver diseases. However, its development is plagued by poor aqueous solubility resulting in poor bioavailability. To circumvent the suboptimal bioavailability of free curcumin, we have develope...

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Detalhes bibliográficos
Main Authors: Bisht, Savita, Khan, Mehtab A, Bekhit, Mena, Bai, Haibo, Cornish, Toby, Mizuma, Masamichi, Rudek, Michelle A, Zhao, Ming, Maitra, Amarnath, Ray, Balmiki, Lahiri, Debomoy, Maitra, Anirban, Anders, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345948/
https://ncbi.nlm.nih.gov/pubmed/21691262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.86
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