A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl(4)-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation

Plant-derived polyphenols such as curcumin hold promise as a therapeutic agent in the treatment of chronic liver diseases. However, its development is plagued by poor aqueous solubility resulting in poor bioavailability. To circumvent the suboptimal bioavailability of free curcumin, we have develope...

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Bibliografiska uppgifter
Huvudupphovsmän: Bisht, Savita, Khan, Mehtab A, Bekhit, Mena, Bai, Haibo, Cornish, Toby, Mizuma, Masamichi, Rudek, Michelle A, Zhao, Ming, Maitra, Amarnath, Ray, Balmiki, Lahiri, Debomoy, Maitra, Anirban, Anders, Robert A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345948/
https://ncbi.nlm.nih.gov/pubmed/21691262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.86
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