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A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl(4)-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation

Plant-derived polyphenols such as curcumin hold promise as a therapeutic agent in the treatment of chronic liver diseases. However, its development is plagued by poor aqueous solubility resulting in poor bioavailability. To circumvent the suboptimal bioavailability of free curcumin, we have develope...

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Bibliografski detalji
Glavni autori: Bisht, Savita, Khan, Mehtab A, Bekhit, Mena, Bai, Haibo, Cornish, Toby, Mizuma, Masamichi, Rudek, Michelle A, Zhao, Ming, Maitra, Amarnath, Ray, Balmiki, Lahiri, Debomoy, Maitra, Anirban, Anders, Robert A
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345948/
https://ncbi.nlm.nih.gov/pubmed/21691262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.86
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