Lipopolysaccharide-Deficient Acinetobacter baumannii Shows Altered Signaling through Host Toll-Like Receptors and Increased Susceptibility to the Host Antimicrobial Peptide LL-37

Infections caused by multidrug-resistant Acinetobacter baumannii have emerged as a serious global health problem. We have shown previously that A. baumannii can become resistant to the last-line antibiotic colistin via the loss of lipopolysaccharide (LPS), including the lipid A anchor, from the oute...

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Detalhes bibliográficos
Main Authors: Moffatt, Jennifer H., Harper, Marina, Mansell, Ashley, Crane, Bethany, Fitzsimons, Timothy C., Nation, Roger L., Li, Jian, Adler, Ben, Boyce, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584870/
https://ncbi.nlm.nih.gov/pubmed/23250952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01362-12
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