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Phospho-sulindac (OXT-328) Inhibits the Growth of Human Lung Cancer Xenografts in Mice: Enhanced Efficacy and Mitochondria Targeting by Its Formulation in Solid Lipid Nanoparticles

PURPOSE: To evaluate the antitumor efficacy of solid lipid nanoparticle–encapsulated phospho-sulindac (SLN-PS) in human lung cancer. METHODS: PS was incorporated into SLNs using the emulsion evaporation technique. We determined the antitumor activity of SLN-PS in cultured lung cancer cells. The perf...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhu, Rongrong, Cheng, Ka-Wing, Mackenzie, Gerardo, Huang, Liqun, Sun, Yu, Xie, Gang, Vrankova, Kveta, Rigas, Basil, Constantinides, Panayiotis P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584452/
https://ncbi.nlm.nih.gov/pubmed/22723123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0801-x
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