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Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts

Pharmacological targeting of breast cancer stem cells (CSCs) is highly promising for the treatment of breast cancer, as the small population of CSCs appears responsible for tumor initiation and progression and also for resistance to conventional treatment. Here we report that the novel phosphosulind...

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Detalhes bibliográficos
Main Authors: Zhu, Caihua, Cheng, Ka-Wing, Ouyang, Nengtai, Huang, Liqun, Sun, Yu, Constantinides, Panayiotis P., Rigas, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621090/
https://ncbi.nlm.nih.gov/pubmed/22653497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1139
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