Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.

We recently identified Vav, the product of the vav proto-oncogene, as a guanine nucleotide exchange factor (GEF) for Ras. Vav is enzymatically activated by lymphocyte antigen receptor-coupled protein tyrosine kinases or independently by diglycerides. To further evaluate the physiological role of Vav...

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Autores principales: Gulbins, E, Coggeshall, K M, Langlet, C, Baier, G, Bonnefoy-Berard, N, Burn, P, Wittinghofer, A, Katzav, S, Altman, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC358445/
https://ncbi.nlm.nih.gov/pubmed/8289830
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