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Activation of p56lck by p72syk through physical association and N-terminal tyrosine phosphorylation.

The p56lck and p59fyn protein tyrosine kinases are important signal transmission elements in the activation of mature T lymphocytes by ligands to the T-cell antigen receptor (TCR)/CD3 complex. The lack of either kinase results in deficient early signaling events, and pharmacological agents that bloc...

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Main Authors: Couture, C, Baier, G, Oetken, C, Williams, S, Telford, D, Marie-Cardine, A, Baier-Bitterlich, G, Fischer, S, Burn, P, Altman, A
Formato: Artigo
Idioma:Inglês
Publicado: 1994
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC359044/
https://ncbi.nlm.nih.gov/pubmed/7518561
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