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Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein.

We recently identified Vav, the product of the vav proto-oncogene, as a guanine nucleotide exchange factor (GEF) for Ras. Vav is enzymatically activated by lymphocyte antigen receptor-coupled protein tyrosine kinases or independently by diglycerides. To further evaluate the physiological role of Vav...

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Published in:Mol Cell Biol
Main Authors: Gulbins, E, Coggeshall, K M, Langlet, C, Baier, G, Bonnefoy-Berard, N, Burn, P, Wittinghofer, A, Katzav, S, Altman, A
Format: Artigo
Language:Inglês
Published: Taylor & Francis 1994
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358445/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8289830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.2.906-913.1994
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