CYP2D6 genotypes, endoxifen levels, and disease recurrence in 224 Filipino and Vietnamese women receiving adjuvant tamoxifen for operable breast cancer

BACKGROUND: While tamoxifen activity is mainly due to endoxifen and the concentration of this active metabolite is, in part, controlled by CYP2D6 metabolic status, clinical correlative studies have produced mixed results. FINDINGS: In an exploratory study, we determined the CYP2D6 metabolic status a...

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Detaylı Bibliyografya
Asıl Yazarlar: Love, Richard R, Desta, Zuerenesay, Flockhart, David, Skaar, Todd, Ogburn, Evan T, Ramamoorthy, Anuradha, Uy, Gemma B, Laudico, Adriano V, Van Dinh, Nguyen, Quang, Le Hong, Van To, Ta, Young, Gregory S, Hade, Erinn, Jarjoura, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2013
Konular:
Short Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584248/
https://ncbi.nlm.nih.gov/pubmed/23476897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-52
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