Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

Oxidative phosphorylation in mitochondria is responsible for 90% of ATP synthesis in most cells. This essential housekeeping function is mediated by nuclear and mitochondrial genes encoding subunits of complex I to V of the respiratory chain. Although complex IV is the best studied of these complexe...

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Autores principales: Quintens, Roel, Singh, Sarvjeet, Lemaire, Katleen, De Bock, Katrien, Granvik, Mikaela, Schraenen, Anica, Vroegrijk, Irene Olga Cornelia Maria, Costa, Veronica, Van Noten, Pieter, Lambrechts, Dennis, Lehnert, Stefan, Van Lommel, Leentje, Thorrez, Lieven, De Faudeur, Geoffroy, Romijn, Johannes Anthonius, Shelton, John Michael, Scorrano, Luca, Lijnen, Henri Roger, Voshol, Peter Jacobus, Carmeliet, Peter, Mammen, Pradeep Puthenveetil Abraham, Schuit, Frans
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584060/
https://ncbi.nlm.nih.gov/pubmed/23460811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056719
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