Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation

We report on a hitherto poorly characterized class of genes that are expressed in all tissues, except in one. Often, these genes have been classified as housekeeping genes, based on their nearly ubiquitous expression. However, the specific repression in one tissue defines a special class of “disallo...

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Autors principals: Thorrez, Lieven, Laudadio, Ilaria, Van Deun, Katrijn, Quintens, Roel, Hendrickx, Nico, Granvik, Mikaela, Lemaire, Katleen, Schraenen, Anica, Van Lommel, Leentje, Lehnert, Stefan, Aguayo-Mazzucato, Cristina, Cheng-Xue, Rui, Gilon, Patrick, Van Mechelen, Iven, Bonner-Weir, Susan, Lemaigre, Frédéric, Schuit, Frans
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012930/
https://ncbi.nlm.nih.gov/pubmed/21088282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.109173.110
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