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How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

The specific phenotype of mature differentiated beta cells not only depends on the specific presence of genes that allow beta cell function but also on the selective absence of housekeeping genes (“disallowed genes”) that would interfere with this function. Recent studies have shown that both histon...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lemaire, Katleen, Granvik, Mikaela, Schraenen, Anica, Goyvaerts, Lotte, Van Lommel, Leentje, Gómez-Ruiz, Ana, in ‘t Veld, Peter, Gilon, Patrick, Schuit, Frans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549890/
https://ncbi.nlm.nih.gov/pubmed/28792951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181651
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