How stable is repression of disallowed genes in pancreatic islets in response to metabolic stress?

The specific phenotype of mature differentiated beta cells not only depends on the specific presence of genes that allow beta cell function but also on the selective absence of housekeeping genes (“disallowed genes”) that would interfere with this function. Recent studies have shown that both histon...

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Publicat a:PLoS One
Autors principals: Lemaire, Katleen, Granvik, Mikaela, Schraenen, Anica, Goyvaerts, Lotte, Van Lommel, Leentje, Gómez-Ruiz, Ana, in ‘t Veld, Peter, Gilon, Patrick, Schuit, Frans
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549890/
https://ncbi.nlm.nih.gov/pubmed/28792951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181651
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