Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

Oxidative phosphorylation in mitochondria is responsible for 90% of ATP synthesis in most cells. This essential housekeeping function is mediated by nuclear and mitochondrial genes encoding subunits of complex I to V of the respiratory chain. Although complex IV is the best studied of these complexe...

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Autors principals: Quintens, Roel, Singh, Sarvjeet, Lemaire, Katleen, De Bock, Katrien, Granvik, Mikaela, Schraenen, Anica, Vroegrijk, Irene Olga Cornelia Maria, Costa, Veronica, Van Noten, Pieter, Lambrechts, Dennis, Lehnert, Stefan, Van Lommel, Leentje, Thorrez, Lieven, De Faudeur, Geoffroy, Romijn, Johannes Anthonius, Shelton, John Michael, Scorrano, Luca, Lijnen, Henri Roger, Voshol, Peter Jacobus, Carmeliet, Peter, Mammen, Pradeep Puthenveetil Abraham, Schuit, Frans
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3584060/
https://ncbi.nlm.nih.gov/pubmed/23460811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056719
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