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NKG2D ligands link oncogenic RAS to innate immunity

RAS is constitutively active in multiple types of tumor cells. We have recently demonstrated that H-RASV12 enhances the translation of ligands for the activating immune receptor NKG2D, hence rendering cells more susceptible to natural killer (NK) cell-mediated lysis. This effect depends on MAPK and...

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Bibliografski detalji
Glavni autori: Ho, Samantha S.W., Gasser, Stephan
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583909/
https://ncbi.nlm.nih.gov/pubmed/23482418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22244
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