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NKG2D ligands link oncogenic RAS to innate immunity
RAS is constitutively active in multiple types of tumor cells. We have recently demonstrated that H-RASV12 enhances the translation of ligands for the activating immune receptor NKG2D, hence rendering cells more susceptible to natural killer (NK) cell-mediated lysis. This effect depends on MAPK and...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583909/ https://ncbi.nlm.nih.gov/pubmed/23482418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22244 |
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