Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val(108/158) Met genotype

BACKGROUND: There is a negative association between the use of antipsychotics and cognitive functioning in bipolar patients, which may be mediated by altered dopamine signaling in selected brain areas, and moderation thereof by genetic sequence variation such as COMT Val(108/158)Met. The interaction...

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Bibliografiske detaljer
Main Authors: Arts, Baer, Simons, Claudia JP, Drukker, Marjan, van Os, Jim
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583705/
https://ncbi.nlm.nih.gov/pubmed/23421957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-13-63
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