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Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val(108/158) Met genotype

BACKGROUND: There is a negative association between the use of antipsychotics and cognitive functioning in bipolar patients, which may be mediated by altered dopamine signaling in selected brain areas, and moderation thereof by genetic sequence variation such as COMT Val(108/158)Met. The interaction...

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Библиографические подробности
Главные авторы: Arts, Baer, Simons, Claudia JP, Drukker, Marjan, van Os, Jim
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583705/
https://ncbi.nlm.nih.gov/pubmed/23421957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-13-63
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