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Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val(108/158) Met genotype

BACKGROUND: There is a negative association between the use of antipsychotics and cognitive functioning in bipolar patients, which may be mediated by altered dopamine signaling in selected brain areas, and moderation thereof by genetic sequence variation such as COMT Val(108/158)Met. The interaction...

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Detalhes bibliográficos
Main Authors: Arts, Baer, Simons, Claudia JP, Drukker, Marjan, van Os, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583705/
https://ncbi.nlm.nih.gov/pubmed/23421957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-13-63
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