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Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val(108/158) Met genotype

BACKGROUND: There is a negative association between the use of antipsychotics and cognitive functioning in bipolar patients, which may be mediated by altered dopamine signaling in selected brain areas, and moderation thereof by genetic sequence variation such as COMT Val(108/158)Met. The interaction...

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Main Authors: Arts, Baer, Simons, Claudia JP, Drukker, Marjan, van Os, Jim
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583705/
https://ncbi.nlm.nih.gov/pubmed/23421957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-13-63
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