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Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val(108/158) Met genotype

BACKGROUND: There is a negative association between the use of antipsychotics and cognitive functioning in bipolar patients, which may be mediated by altered dopamine signaling in selected brain areas, and moderation thereof by genetic sequence variation such as COMT Val(108/158)Met. The interaction...

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主要な著者: Arts, Baer, Simons, Claudia JP, Drukker, Marjan, van Os, Jim
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583705/
https://ncbi.nlm.nih.gov/pubmed/23421957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-13-63
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