Загрузка...
Targeted inhibition of heat shock protein 90 disrupts multiple oncogenic signaling pathways, thus inducing cell cycle arrest and programmed cell death in human urinary bladder cancer cell lines
BACKGROUND: Geldanamycin (GA) can be considered a relatively new component with a promising mode of action against human malignancies. It specifically targets heat shock protein 90 (Hsp90) and interferes with its function as a molecular chaperone. METHODS: In this study, we have investigated the eff...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2013
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583703/ https://ncbi.nlm.nih.gov/pubmed/23394616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-11 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|