3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants

BACKGROUND: Urinary bladder cancer is one of the most fatal and expensive diseases of industrialized world. Despite the strenuous efforts, no seminal advances have been achieved for its clinical management. Given the importance of metabolic reprogramming in cancer cell survival and growth, we have h...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Konstantakou, Eumorphia G., Voutsinas, Gerassimos E., Velentzas, Athanassios D., Basogianni, Aggeliki-Stefania, Paronis, Efthimios, Balafas, Evangelos, Kostomitsopoulos, Nikolaos, Syrigos, Konstantinos N., Anastasiadou, Ema, Stravopodis, Dimitrios J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511243/
https://ncbi.nlm.nih.gov/pubmed/26198749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0399-9
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