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Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression

Androgen ablation therapy represents the first line of therapeutic intervention in men with advanced or recurrent prostate tumors. However, the incomplete efficacy and lack of durable response to this clinical strategy highlights an urgent need for alternative treatment options to improve patient ou...

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Hlavní autoři: HE, SUQIN, ZHANG, CHAOHUA, SHAFI, AYESHA A., SEQUEIRA, MANUEL, ACQUAVIVA, JAIME, FRIEDLAND, JULIE C., SANG, JIM, SMITH, DONALD L., WEIGEL, NANCY L., WADA, YUMIKO, PROIA, DAVID A.
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583620/
https://ncbi.nlm.nih.gov/pubmed/23152004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1698
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