Anthrax Lethal Factor Activates K(+) Channels To Induce IL-1β Secretion in Macrophages

Anthrax lethal toxin (LeTx) is a virulence factor of Bacilillus anthracis that is a bivalent toxin, containing lethal factor (LF) and protective Ag proteins, which causes cytotoxicity and altered macrophage function. LeTx exposure results in early K(+) efflux from macrophages associated with caspase...

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Autors principals: Thomas, Johnson, Epshtein, Yulia, Chopra, Arun, Ordog, Balazs, Ghassemi, Mahmood, Christman, John W., Nattel, Stanley, Cook, James L., Levitan, Irena
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583536/
https://ncbi.nlm.nih.gov/pubmed/21421849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001078
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