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Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer’s disease: a stochastic modelling approach
BACKGROUND: Alzheimer’s disease (AD) is the most frequently diagnosed neurodegenerative disorder affecting humans, with advanced age being the most prominent risk factor for developing AD. Despite intense research efforts aimed at elucidating the precise molecular underpinnings of AD, a definitive a...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583291/ https://ncbi.nlm.nih.gov/pubmed/22748062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-32 |
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