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Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy
AIMS: Duchenne muscular dystrophy (DMD) is a muscle disease with serious cardiac complications. Changes in Ca(2+) homeostasis and oxidative stress were recently associated with cardiac deterioration, but the cellular pathophysiological mechanisms remain elusive. We investigated whether the activity...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583259/ https://ncbi.nlm.nih.gov/pubmed/23263329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs425 |
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