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Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans
AIMS: Human genome-wide association studies (GWAS) of hypertension identified only few susceptibility loci with large effect that were replicated across populations. The vast majority of genes detected by GWAS has small effect and the regulatory mechanisms through which these genetic variants cause...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3583256/ https://ncbi.nlm.nih.gov/pubmed/23118132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs329 |
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