Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat

The spontaneously hypertensive rat (SHR) is a widely used rodent model of hypertension and metabolic syndrome. Previously we identified thousands of cis-regulated expression quantitative trait loci (eQTLs) across multiple tissues using a panel of rat recombinant inbred (RI) strains derived from Brow...

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Main Authors: Morrissey, Catherine, Grieve, Ian C., Heinig, Matthias, Atanur, Santosh, Petretto, Enrico, Pravenec, Michal, Hubner, Norbert, Aitman, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
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Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3217321/
https://ncbi.nlm.nih.gov/pubmed/21846806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00210.2010
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