Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

Two-thirds of gene promoters in mammals are associated with regions of non-methylated DNA, called CpG islands (CGIs), which counteract the repressive effects of DNA methylation on chromatin. In cold-blooded vertebrates, computational CGI predictions often reside away from gene promoters, suggesting...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Long, Hannah K, Sims, David, Heger, Andreas, Blackledge, Neil P, Kutter, Claudia, Wright, Megan L, Grützner, Frank, Odom, Duncan T, Patient, Roger, Ponting, Chris P, Klose, Robert J
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2013
Предметы:
Genes and Chromosomes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583005/
https://ncbi.nlm.nih.gov/pubmed/23467541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00348
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы