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The elephant shark methylome reveals conservation of epigenetic regulation across jawed vertebrates

Background: Methylation of CG dinucleotides constitutes a critical system of epigenetic memory in bony vertebrates, where it modulates gene expression and suppresses transposon activity. The genomes of studied vertebrates are pervasively hypermethylated, with the exception of regulatory elements suc...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Peat, Julian R., Ortega-Recalde, Oscar, Kardailsky, Olga, Hore, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437953/
https://ncbi.nlm.nih.gov/pubmed/28580133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11281.1
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