Development of K562 cell clones expressing β-globin mRNA carrying the β(0)39 thalassaemia mutation for the screening of correctors of stop-codon mutations

Nonsense mutations, giving rise to UAA, UGA and UAG stop codons within the coding region of mRNAs, promote premature translational termination and are the leading cause of approx. 30 % of inherited diseases, including cystic fibrosis, Duchenne muscular dystrophy and thalassaemia. For instance, in β(...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Salvatori, Francesca, Cantale, Vera, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Bianchi, Nicoletta, Borgatti, Monica, Feriotto, Giordana, Destro, Federica, Canella, Alessandro, Breda, Laura, Rivella, Stefano, Gambari, Roberto
格式: Artigo
語言:Inglês
出版: 2009
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582994/
https://ncbi.nlm.nih.gov/pubmed/19216718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BA20080266
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍