Angiotensin II drives the production of tumor-promoting macrophages

Macrophages frequently infiltrate tumors and can enhance cancer growth, yet the origins of the macrophage response are not well understood. Here we address molecular mechanisms of macrophage production in a conditional mouse model of lung adenocarcinoma. We report that over-production of the peptide...

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Detalhes bibliográficos
Main Authors: Cortez-Retamozo, Virna, Etzrodt, Martin, Newton, Andita, Ryan, Russell, Pucci, Ferdinando, Sio, Selena W., Kuswanto, Wilson, Rauch, Philipp J., Chudnovskiy, Aleksey, Iwamoto, Yoshiko, Kohler, Rainer, Marinelli, Brett, Gorbatov, Rostic, Wojtkiewicz, Gregory, Panizzi, Peter, Mino-Kenudson, Mari, Forghani, Reza, Figueiredo, Jose-Luiz, Chen, John W., Xavier, Ramnik, Swirski, Filip K., Nahrendorf, Matthias, Weissleder, Ralph, Pittet, Mikael J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582771/
https://ncbi.nlm.nih.gov/pubmed/23333075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.10.015
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