Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

A current paradigm states that monocytes circulate freely and patrol blood vessels but differentiate irreversibly into dendritic cells (DCs) or macrophages upon tissue entry. Here we show that bona fide undifferentiated monocytes reside in the spleen and outnumber their equivalents in circulation. T...

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Bibliografski detalji
Glavni autori: Swirski, Filip K., Nahrendorf, Matthias, Etzrodt, Martin, Wildgruber, Moritz, Cortez-Retamozo, Virna, Panizzi, Peter, Figueiredo, Jose-Luiz, Kohler, Rainer H., Chudnovskiy, Aleksey, Waterman, Peter, Aikawa, Elena, Mempel, Thorsten R., Libby, Peter, Weissleder, Ralph, Pittet, Mikael J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803111/
https://ncbi.nlm.nih.gov/pubmed/19644120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1175202
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