Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner

BACKGROUND: Chromosome 17q21.31 contains a common inversion polymorphism of approximately 900 kb in populations with European ancestry. Two divergent MAPT haplotypes, H1 and H2 are described with distinct linkage disequilibrium patterns across the region reflecting the inversion status at this locus...

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Autors principals: de Jong, Simone, Chepelev, Iouri, Janson, Esther, Strengman, Eric, van den Berg, Leonard H, Veldink, Jan H, Ophoff, Roel A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582489/
https://ncbi.nlm.nih.gov/pubmed/22950410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-458
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