Evolutionary Toggling of the MAPT 17q21.31 Inversion Region

Using comparative sequencing approaches, we investigated the evolutionary history of the European-enriched 17q21.31 MAPT inversion polymorphism. We present a detailed, BAC-based sequence assembly of the inverted human H2 haplotype and contrast it with the sequence structure and genetic variation of...

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Detalhes bibliográficos
Main Authors: Zody, Michael C., Jiang, Zhaoshi, Fung, Hon-Chung, Antonacci, Francesca, Hillier, LaDeana W., Cardone, Maria Francesca, Graves, Tina A., Kidd, Jeffrey M., Cheng, Ze, Abouelleil, Amr, Chen, Lin, Wallis, John, Glasscock, Jarret, Wilson, Richard K., Reily, Amy Denise, Duckworth, Jaime, Ventura, Mario, Hardy, John, Warren, Wesley C., Eichler, Evan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684794/
https://ncbi.nlm.nih.gov/pubmed/19165922
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