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Structural Diversity and African Origin of the 17q21.31 Inversion Polymorphism
The 17q21.31 inversion polymorphism exists either as direct (H1) or inverted (H2) haplotypes with differential predispositions to disease and selection. We investigated its genetic diversity in 2700 individuals with an emphasis on African populations. We characterize eight structural haplotypes that...
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| Главные авторы: | , , , , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408829/ https://ncbi.nlm.nih.gov/pubmed/22751100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2335 |
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