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Advances in PET Imaging of P-Glycoprotein Function at the Blood-Brain Barrier

[Image: see text] Efflux transporter P-glycoprotein (P-gp) at the blood-brain barrier (BBB) restricts substrate compounds from entering the brain and may thus contribute to pharmacoresistance observed in patient groups with refractory epilepsy and HIV. Altered P-gp function has also been implicated...

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Detalhes bibliográficos
Main Authors: Syvänen, Stina, Eriksson, Jonas
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582299/
https://ncbi.nlm.nih.gov/pubmed/23421673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3001729
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