P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender

PURPOSE: P-glycoprotein (Pgp) is an efflux transporter involved in transport of several compounds across the blood–brain barrier (BBB). Loss of Pgp function with increasing age may be involved in the development of age-related disorders, but this may differ between males and females. Pgp function ca...

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Библиографические подробности
Главные авторы: van Assema, Daniëlle M. E., Lubberink, Mark, Boellaard, Ronald, Schuit, Robert C., Windhorst, Albert D., Scheltens, Philip, Lammertsma, Adriaan A., van Berckel, Bart N. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer-Verlag 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492696/
https://ncbi.nlm.nih.gov/pubmed/22476967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-012-0556-0
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