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P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender

PURPOSE: P-glycoprotein (Pgp) is an efflux transporter involved in transport of several compounds across the blood–brain barrier (BBB). Loss of Pgp function with increasing age may be involved in the development of age-related disorders, but this may differ between males and females. Pgp function ca...

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Main Authors: van Assema, Daniëlle M. E., Lubberink, Mark, Boellaard, Ronald, Schuit, Robert C., Windhorst, Albert D., Scheltens, Philip, Lammertsma, Adriaan A., van Berckel, Bart N. M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492696/
https://ncbi.nlm.nih.gov/pubmed/22476967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-012-0556-0
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