Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling

Exogenous dietary fat can induce obesity and promote diabetes, but endogenous fat production is not thought to affect skeletal muscle insulin resistance, an antecedent of metabolic disease. Unexpectedly, the lipogenic enzyme fatty acid synthase (FAS) was increased in the skeletal muscle of mice with...

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Bibliografiske detaljer
Main Authors: Funai, Katsuhiko, Song, Haowei, Yin, Li, Lodhi, Irfan J., Wei, Xiaochao, Yoshino, Jun, Coleman, Trey, Semenkovich, Clay F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582136/
https://ncbi.nlm.nih.gov/pubmed/23376793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65726
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